Table 5.

Criterion-related validity and clinical validity of the simplified Chinese version of quality of life questionnaire (QLQ-C30)

QLQ-C30 domains	Criterion-related validity, correlations with QLICP-GM				Clinical validity, comparisons of two treatments
	PHD	PSD	SOD	SSD	Surgery		Chemotherapy		t	P
					Mean	SD	Mean	SD
Physical functioning	0.41	0.22	0.16	0.23	78.35	19.22	75.43	19.31	0.94	0.350
Role functioning	0.39	0.29	0.25	0.37	64.32	30.36	53.65	25.34	2.33	0.021
Emotional functioning	0.26	0.67	0.37	0.39	69.94	21.26	65.26	22.72	1.31	0.193
Cognitive functioning	0.31	0.44	0.32	0.44	75.21	18.56	68.04	23.53	2.09	0.039
Social functioning	0.27	0.40	0.38	0.32	65.19	24.05	55.48	25.62	2.41	0.017
Global health status	0.35	0.23	0.20	0.28	56.52	23.67	53.36	26.60	0.77	0.443
Fatigue	−0.43	−0.37	−0.22	−0.55	33.19	21.83	44.14	19.13	−3.28	0.001
Nausea and vomiting	−0.14	−0.28	−0.21	−0.55	17.30	22.08	28.70	26.42	−2.89	0.004
Pain	−0.36	−0.38	−0.22	−0.53	29.11	23.03	39.50	24.92	−2.67	0.008
Dyspnea	−0.22	−0.27	−0.16	−0.35	17.08	22.50	28.31	27.03	−2.80	0.006
Insomnia	−0.36	−0.32	−0.25	−0.39	30.38	26.79	36.07	30.30	−1.23	0.221
Appetite loss	−0.32	−0.30	−0.17	−0.47	30.38	24.57	42.92	26.92	−3.00	0.003
Constipation	−0.07a	−0.14	−0.12	−0.31	23.21	23.48	31.46	27.54	−1.98	0.050
Diarrhea	−0.08a	−0.12	0.00a	−0.27	16.03	23.18	15.28	22.33	0.20	0.839
Financial difficulties	−0.14	−0.33	−0.46	−0.23	56.54	33.06	58.90	32.16	−0.45	0.656

The numbers in bold are the correlation coefficients between the same/similar domians of the two instruments.

^aCorrelations: no statistical significance (P > 0.05) and others significant (P < 0.05).

PHD, physical domain; PSD, psychological domain; SOD, social domain; SSD, common symptom/side-effects domain; QLICP-GM, quality of life instruments for cancer patients-general module; SD, standard deviation.