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. 2008 Jul 24;19(12):2053–2060. doi: 10.1093/annonc/mdn417

Table 8.

Responsiveness of simplified Chinese version of quality of life questionnaire (QLQ-C30) for measuring quality of life of patients with colorectal, stomach, and head and neck cancer (n = 170)

Domains (subscales/items) Pre-treatment Post-treatment Differences SRM t P
Mean SD Mean SD Mean SD
Physical functioning 71.23 23.43 83.87 17.07 −12.64 17.32 0.73 −9.77 <0.0001
Role functioning 52.04 29.72 62.59 26.70 −10.56 26.48 0.40 −5.35 <0.0001
Emotional functioning 64.48 21.70 66.68 18.08 −2.20 16.68 0.13 −1.77 0.08
Cognitive functioning 67.23 23.70 68.25 23.08 −1.02 18.54 0.06 −0.74 0.46
Social functioning 56.02 28.45 53.89 27.75 2.13 24.22 0.09 1.18 0.24
Global health status 53.42 24.41 60.44 26.10 −7.02 23.10 0.30 −4.06 <0.0001
Fatigue 45.50 25.44 41.31 21.62 4.19 22.36 0.19 2.51 0.01
Nausea and vomiting 24.58 24.82 18.62 22.71 5.96 24.26 0.25 3.29 0.001
Pain 36.39 26.22 32.69 22.72 3.70 23.54 0.16 2.11 0.04
Dyspnea 24.81 27.32 14.26 22.29 10.56 25.28 0.42 5.60 <0.0001
Insomnia 37.27 29.06 26.97 23.44 10.30 23.50 0.44 5.85 <0.0001
Appetite loss 41.11 29.08 36.85 27.41 4.26 29.70 0.14 1.92 0.06
Constipation 26.26 26.20 21.42 23.05 4.84 24.51 0.20 2.64 0.01
Diarrhoea 21.79 24.03 23.28 25.69 −1.49 25.44 0.06 −0.78 0.43
Financial difficulties 58.29 31.97 62.20 63.83 −3.91 62.04 0.06 −0.84 0.40

SD, standard deviation; SRM, standardized response mean.