Figure 3. Psn-induced wing notching is suppressed by loss-of-function mutations in Cam.

A) Overexpression of wild type Psn under the control of cut-GAL4 induces a wing notching phenotype in flies (500 µm scale bar). B) The loss of a single Cam allele suppresses the Psn-induced wing phenotype (500 µm scale bar). C) Quantification of the penetrance of Psn-induced wing notching phenotype and the suppression of this phenotype by two loss-of-function mutations in Cam (Cam null and Cam hypomorph). Penetrance was scored based on the presence of at least one wing margin notch. Asterisks denote significant differences in expected penetrance relative to the original cut-Psn recombinant as determined by the χ² test.