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. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: Ann N Y Acad Sci. 2009 Jan;1152:174–186. doi: 10.1111/j.1749-6632.2008.03994.x

FIGURE 7.

FIGURE 7

Role of inwardly rectifying potassium channels (Kir) in spontaneous and agonist-controlled calcium signaling and secretion. (A) Activation of Kir channels by ET-1 and apomorphine. (B and C) Apomorphine-induced inhibition of basal PRL release (B) and calcium transients (C) in cells with inhibited Kir channels with cesium. Note increase in [Ca2+]i after application of cesium. Horizontal bars indicate duration of application of 5 mM cesium and gray areas represent duration of apomorphine treatment. Arrow indicates time of TRH addition.