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. Author manuscript; available in PMC: 2009 Aug 27.
Published in final edited form as: Toxicol Pathol. 2009 Jun 17;37(5):629–643. doi: 10.1177/0192623309339605

Figure 1.

Figure 1

Representative photomicrographs demonstrating renal alterations in control, gentamicin (Gen)-, or cisplatin (Cis)-treated rats. (A) Neither tubular epithelial cell necrosis nor (B) apoptosis were found in the S1/S2 segments in eighty-day-old, saline-treated control rats in the Gen study. (C) Tubular epithelial cell necrosis and (D) apoptosis were found in the S1/S2 segments in eighty-day-old rats treated with 100 mg/kg/day of Gen for fourteen days. (E) Neither tubular epithelial cell necrosis nor (F) apoptosis were found in the tubular epithelial cells of the collecting ducts or the loop of Henle of saline-treated, forty-day-old control rats in the Cis study. (G) Tubular epithelial cell necrosis and (H) apoptosis were found in the tubular epithelial cells of the loop of Henle in forty-day-old rats treated with 3 mg/kg Cis. All figures ×400.