Table II. Medical and treatment-related characteristics by participation status on ETS reduction trial among pediatric cancer patients.
| Total (N = 153) |
Participants (n = 117) |
Non-participants (n = 36) |
P-Value* | |
|---|---|---|---|---|
| n (%) | n (%) | n (%) | ||
| Child cancer diagnosis | ||||
| CNS Tumor | 16 (10) | 8 (7) | 8 (22) | |
| Leukemia / Lymphoma | 96 (63) | 77 (66) | 19 (53) | |
| Solid Tumor | 41 (27) | 32 (27) | 9 (25) | 0.030 |
| Time since diagnosis (days) | ||||
| 0-30 days | 2 (1) | 2 (2) | 0 (0) | |
| 31-90 days | 73 (48) | 56 (48) | 17 (47) | |
| 91-180 days | 29 (19) | 22 (19) | 7 (20) | |
| >180 days | 49 (32) | 37 (31) | 12 (33) | 0.754 |
| History of relapse (prior to recruitment) | ||||
| No | 137 (90) | 104 (89) | 33 (92) | |
| Yes | 16 (10) | 13 (11) | 3 (8) | 0.764 |
| Number of days hospitalized (30 days prior to recruitment) | ||||
| 0 days | 91 (60) | 67 (57) | 24 (67) | |
| 1-7 days | 43 (28) | 34 (29) | 9 (25) | |
| 8-14 days | 16 (10) | 14 (12) | 2 (5) | |
| > 14 days | 3 (2) | 2 (2) | 1 (3) | 0.384 |
| History of surgery (prior to recruitment) | ||||
| No | 91 (59) | 75 (64) | 16 (44) | |
| Yes | 62 (41) | 42 (36) | 20 (56) | 0.036 |
| History of chemotherapy (prior to recruitment) | ||||
| No | 10 (7) | 4 (3) | 6 (17) | |
| Yes | 143 (93) | 113 (97) | 30 (83) | 0.012 |
| History of radiation (prior to recruitment) | ||||
| No | 121 (79) | 96 (82) | 25 (69) | |
| Yes | 32 (21) | 21 (18) | 11 (31) | 0.104 |
| Planned surgery (post recruitment) | ||||
| No | 112 (73) | 83 (71) | 29 (81) | |
| Yes | 41 (27) | 34 (29) | 7 (19) | 0.265 |
| Planned chemotherapy (post recruitment) | ||||
| No | 21 (14) | 16 (14) | 5 (14) | |
| Yes | 132 (86) | 101 (86) | 31 (86) | 0.999 |
| Planned radiation (post recruitment) | ||||
| No | 111 (73) | 91 (78) | 20 (56) | |
| Yes | 42 (27) | 26 (22) | 16 (44) | 0.009 |
| Total number of therapeutic and non-therapeutic protocols enrolled on (prior to recruitment) | ||||
| No protocols | 26 (17) | 21 (18) | 5 (14) | |
| 1 protocol | 46 (30) | 32 (28) | 14 (39) | |
| 2 protocols | 34 (22) | 25 (21) | 9 (25) | |
| 3-6 protocols | 47 (31) | 39 (33) | 8 (22) | 0.484 |
*
T-test was used for continuous variables, Pearson chi-square test or Fisher's exact test was used for nominal categorical variables, and Mantel-Haenszel chi-square test was used for ordered category variables.