Table 2.
1H Magnetic ResonanceSpectroscopic Imaging Metabolite Ratios From Frontal and Posterior White Matter Voxels*
| Controls (n=18) |
AD (n=14) |
SIVO(n=8) |
||||
|---|---|---|---|---|---|---|
| Frontal | Posterior | Frontal | Posterior | Frontal | Posterior | |
| NAA/Cho | 1.9±0.4 | 2.6±0.4 | 1.7±0.4 | 2.1±0.4 | 1.7±0.3 | 2.6±0.6 |
| NAA/Cr | 3.3±0.6 | 3.0±0.4 | 2.9±0.3 | 2.9±0.4 | 2.5±0.5† | 2.9±0.4 |
| Cho/Cr | 1.8±0.4 | 1.2±0.2 | 1.8±0.4 | 1.4±0.4 | 1.5±0.5 | 1.2±0.3 |
*
*AD indicates Alzheimer's disease; SIVD, subcortical ischemie vascular dementia; NAA, ti-acetylaspartate; Cho, choline-containing metabolites; and Cr, sum of creatine plus phosphocreatine. Values are means±SDs.
†
Significant group by region effect vs controls by repeated analysis of variance measures.