Table 4.
Correlations (Pearson’s r values) between clinical covariates (and change over 1 year) and the rates of hippocampal atrophy in percent per year
AD |
N | MCI |
N | Normal |
N | ||||
---|---|---|---|---|---|---|---|---|---|
Left | Right | Left | Right | Left | Right | ||||
MMSE | −0.149 | 0.021 | 97 | 0.017 | 0.023 | 245 | −0.144a | −0.149a | 148 |
Change in MMSE | 0.039 | 0.098 | 97 | 0.195b | 0.133a | 245 | −0.184a | −0.022 | 148 |
gCDR | −0.077 | 0.015 | 97 | N.A. | N.A. | 245 | N.A. | N.A. | 148 |
Change in gCDR | −0.193a | −0.104 | 97 | −0.099 | −0.072 | 245 | −0.059 | −0.040 | 148 |
sobCDR | 0.031 | 0.019 | 97 | −0.006 | 0.011 | 245 | 0.013 | 0.062 | 148 |
Change in sobCDR | −0.093 | −0.150 | 97 | −0.131a | −0.112a | 245 | −0.144a | 0.023 | 147 |
N.A. (not applicable) is reported for the global CDR in the MCI and AD groups because all MCI and AD patients had the same global CDR values (0.5 and 0 respectively). One normal subject did not have a sum-of-boxes CDR follow-up score, hence the 147 subjects for that one measure.
p<0.05.
p<0.01.