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. 2008 Apr 28;17(15):2357–2369. doi: 10.1093/hmg/ddn136

Figure 8.

Figure 8.

Hair density (bars filled with dots) and full skin thickness (bars with diagonal lines) in male (M) and female (F) transgenic mice expressing progerin (K14-progerin), transgenic mice expressing wild-type human lamin A (K14-lamin A) and non-transgenic mice (WT) on Lmna−/−, Lmna+/− and Lmna+/+ backgrounds. Hair density and skin thickness were scored on a scale of 1 (lowest) to 5 (highest). Values are means ± SD for n = 5 to 6 mice. Lmna−/− mice expressing either progerin or wild-type lamin A or without a transgene had significantly decreased hair density and full-skin thickness compared to Lmna+/− and Lmna+/+ mice.