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Overexpression of follistatin does not improve disease features of severe SMA mice. (A) Average total righting time in follistatin-negative (n = 8) and follistatin-positive SMA mice (n = 17). (B) Kaplan–Meier survival curves comparing follistatin-negative and follistatin-positive SMA mice. Median survival in follistatin-negative SMA mice was 13 and median survival in follistatin-positive mice was 14 (Log rank P = 0.6, n = 11 follistatin-negative, 25 follistatin-positive SMA mice).
