. Author manuscript; available in PMC: 2010 Aug 1.

Published in final edited form as: Clin Immunol. 2009 May 22;132(2):174–183. doi: 10.1016/j.clim.2009.04.010

Table 3.

Genes in JAK-STAT pathway upregulated in the peripheral blood of patients with sarcoidosis.

Gene symbols	Gene titles	Number of probe sets	Mean fold increase	q-value^*
IFNAR1	interferon (alpha, beta and omega) receptor 1	3	1.25	0.029
IFNAR2	interferon (alpha, beta and omega) receptor 2	2	1.28	0.028
IFNGR2	interferon γreceptor 2 (interferon γ transducer 1)	1	1.11	0.029

JAK1	Janus kinase 1 (a protein tyrosine kinase)	3	0.88	0.039
JAK2	Janus kinase 2 (a protein tyrosine kinase)	3	1.38	0.029

STAT1	signal transducer and activator of transcription 1, 91kDa	6	1.99	0.001
STAT2	signal transducer and activator of transcription 2, 113kDa	3	1.44	0.029
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	4	1.38	0.029

Number of Probe Sets reflects the characteristics of the Affymetrix U133 Plus 2.0 array which detects some transcripts with discrete probes that identify different portions of the transcript.

The maximum q-value in case of multiple probe sets