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. 2000 Apr 8;320(7240):985–986. doi: 10.1136/bmj.320.7240.985

Table.

Likelihood ratios for screening tests for left ventricular systolic dysfunction. Any combination of tests is defined as being positive if any of the individual components are positive

Screening criteria Specificity (%) Sensitivity (%) Likelihood ratio if test negative Likelihood ratio if test positive Posterior probability if test negative* (%) Posterior probability if test positive* (%)
Myocardial infarction 91 33 0.74 3.62 26 63
Electrocardiogram 87 41 0.68 3.13 24 60
Chest radiograph§ 45 65 0.79 1.17 27 36
Brain natriuretic peptide 34 88 0.35 1.32 15 38
Myocardial infarction or
 Electrocardiogram 82 61 0.48 3.29 19 61
 Chest radiograph 37 83 0.46 1.32 18 38
 Brain natriuretic peptide 27 90 0.38 1.23 15 37
Myocardial infarction or electrocardiogram or
 Chest radiograph 31 83 0.53 1.22 20 36
 Brain natriuretic peptide 22 91 0.42 1.17 16 35
Myocardial infarction or chest radiograph or brain natriuretic peptide 14 91 0.62 1.06 23 33
Any test 11 92 0.78 1.03 27 33
*

Prevalence (prior probability) of left ventricular systolic dysfunction assumed to be 32%. 

Positive if there is a history of myocardial infarction. 

Positive if Q waves, bundle branch block, left ventricular hypertrophy, or T wave present. 

§

Positive if pulmonary oedema or cardiomegaly present. 

Positive if concentration >17.9 pg/ml.