. 2009 Jan 29;26(4):937–949. doi: 10.1093/molbev/msp018

Table 4.

Polymorphisms and Fixed Differences for Nonsynonymous and Synonymous Sites

Comparison	Site	Polymorphisms^a	Fixed Differences^b	P Value
Human and chimp together	Nonsynonymous	15 (16)	23	0.08 (0.08)
Human and chimp together	Synonymous	7	28
Human alone	Nonsynonymous	12 (13)	21	0.17 (0.10)
Human alone	Synonymous	6	27
Chimp alone	Nonsynonymous	3	21	0.61
Chimp alone	Synonymous	1	23

Thirteen replacement polymorphisms occur in humans. One of them occurs uniquely in the background of the haplotype containing the premature stop. The M–K test was computed including and excluding that replacement change (numbers of polymorphisms and P values in parentheses).

All fixed differences are in comparison with the orangutan sequence.