Table I.
Nugent score and single locus case control results in (A) white women and (B) black women
| Gene | Location | Nugent P-value | Modela | Case–control OR (95% CI), P-value |
|
|---|---|---|---|---|---|
| Unadjusted for smoking | Adjusted for smoking | ||||
| (A) White women | |||||
| CRH-BP | 15033 | 0.02 | TT versus AA/AT | 5.4b (1.5–19.1), <0.01 | 5.0 (1.4–18.0), 0.01 |
| CRH-R1 | 9-50 | 0.02 | AA versus AG/GG | 4.0b (1.4–11.9), 0.01 | 3.9 (1.3–11.7), 0.02 |
| (B) Black women | |||||
| CRH | 3362 | 5 × 10−3 | AG versus AA | 0.2b (0.03–0.68), 0.01 | 0.2b (0.03–0.94), 0.04 |
| CRH | −1667 | 5 × 10−3 | CT versus CC | 0.2b (0.03–0.68), 0.01 | 0.2b (0.03–0.94), 0.04 |
aSecond genotype given indicates the referent group.
bIndicates that likelihood ratio test was significant.