Table 2. X-ray induced chromosomal aberrations in primary human fibroblasts irradiated in G2 phase of the cell cycle.
Cell line | X-ray dose (Gy) | Breaks/cell | Interchanges/cell | Total breaks/cell* | Induced breaks/cell** |
VH10 (wt) | 0 | 0.01 | 0 | 0.01 | 0 |
0.1 | 0.10 | 0 | 0.10 | 0.09 | |
0.25 | 0.20 | 0 | 0.20 | 0.19 | |
VU1174-F (RBS) | 0 | 0.02 | 0 | 0.02 | 0 |
0.1 | 0.10 | 0 | 0.10 | 0.08 | |
0.25 | 0.24 | 0 | 0.24 | 0.22 |
Frequency of total breaks estimated by counting one chromatid interchange as two breaks.
Induced break frequency is estimated by subtracting values obtained in control from those obtained after irradiating cells.