Skip to main content
. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2009 Jan 15;29(4):480–487. doi: 10.1161/ATVBAHA.108.181925

Figure 4.

Figure 4

Effect of Nox1 expression on proliferation, migration and extracellular matrix (ECM) production. A. Growth curves were obtained from WT, Nox1y/- and OE cells. B. Cell migration was assessed using the modified Boyden chamber assay. Quiescent VSMCs were treated with 10 ng/ml PDGF for 3 h. C. Measurement of collagen I and fibronectin in culture media. Serum-starved VSMCs were maintained in the presence of 50 μg/mL ascorbic acid and β-aminopropionitrile with or without 10 ng/ml PDGF for 72 h. Media was collected and subjected to Western blotting. Representative immunoblots are shown in C. Values are means±SE of 6 (A) and 3 (B and C) independent observations. * Significantly different from corresponding control (p < 0.05).