Table 2.

Effects of TAC on Collagen Composition in WT vs. SPARC Null Mice

	Control		TAC
	WT	SPARC Null	WT	SPARC Null
Total Collagen mg/gDW	1.63 ± 0.08	1.27 ± 0.04^*	2.01 ± 0.2^*^#	1.96 ± 0.16^*^#
Insoluble Collagen mg/gDW	1.48 ± 0.06	1.1 ± 0.04^*	1.99 ± 0.18^*^#	1.69 ± 0.16^*^#^$
% of Total	91 ± 1	87 ± 1^*	99 ± 2^*^#	86 ± 2^*^$
Soluble Collagen mg/gDW	0.14 ± 0.04	0.17 ± 0.02	0.05 ± 0.01^*^#	0.28 ± 0.06^*^#^$
% of Total	9 ± 1	13 ± 1^*	1 ± 2^*^#	14 ± 2^*^$

Abbreviations: Collagen is measured as Hydroxyproline, TAC = transverse aortic constriction, SPARC = Secreted Protein Acidic and Rich in Cysteine, Data are mean ± SEM

= p < 0.05 vs. WT Control

= p <, 0.05 vs. SPARC Null

= p <, 0.05 vs. WT TAC.