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Fitted mean (±SEM) craving, withdrawal, and PA and NA due to nicotine versus placebo patch use on abstinent days, by time of day. Comparisons are between responses to nicotine patch versus placebo patch while abstinent. Participants were those who were abstinent at least 1 day during the nicotine patch week and 1 day during the placebo patch week (n = 79). *p < .05; **p < .01; ***p < .001 for the difference at each timepoint between nicotine patch and placebo patch.
