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DON, T-2, and ricin time-dependently alter RNase mRNA expression in RAW 264.7 cells. Cells were treated with DON (1000 ng/ml), (A, D) T-2 (160 ng/ml), (B, E) and ricin (320 ng/ml) (C, F) for indicated time interval. Total RNA was analyzed for RNase 6 and RNase L expression analyzed by real-time PCR. Data are means ± SEM (n = 8) pooled from two separate experiments. Bars without same letter differ (p < 0.05).
