FIG. 5.

Distinct responses to different types of genotoxins 4 h after treatment start. Gene expression ratios (s. “Ratio” scale on the left) of functional gene subgroups genes in studies from six partners (#1, 2, 3, 4, 8, 9) are shown after one-dimensional Euclidian clustering for genes, separate for the 4-h (A) and 24-h (B) time point. % Cell number is illustrated at the top of each heatmap according to the leftmost color scale. The main functions of the genes listed left to the heatmaps are indicated aside. Samples from different compounds are separated by yellow lines. Study numbers are given below the heat maps. The consistent upregulation of HIST1H2AC is highlighted in the taxol samples with a yellow frame. Cp (cisplatin), Etop (etoposide), Txl (taxol), NaCl (sodium chloride).