Table 2.

Fisher’s combined p values for risk alleles in lupus-associated MECP2 SNPs in all three lupus cohorts reported.

SNP	Risk allele	Odds ratio (95% CI)			Fisher combined p value
		Korean*	European-derived 1*	European-derived 2**
rs2075596	A	1.49 (1.24–1.80)	1.28 (1.09–1.52)	1.35 (1.17–1.57)	1.57×10−9
rs3027933	C	1.48 (1.23–1.79)	1.30 (1.10–1.53)	1.38 (1.19–1.60)	2.90×10−10
rs17435	T	1.58 (1.31–1.90)	1.29 (1.11–1.49)	1.22 (1.07–1.38)	1.45×10−9
rs1624766	G	1.50 (1.24–1.82)	1.28 (1.10–1.48)	1.21 (1.06–1.37)	3.76×10−8
rs1734787	C	1.55 (1.29–1.87)	1.32 (1.12–1.56)	1.35 (1.17–1.56)	6.65×10−11
rs1734791	A	1.51 (1.25–1.82)	1.31 (1.11–1.54)	1.37 (1.18–1.59)	1.52×10−10
rs1734792	A	1.53 (1.27–1.83)	1.31 (1.11–1.54)	1.37 (1.18–1.58)	9.67×10−11
rs2239464	A	1.51 (1.25–1.82)	1.24 (1.07–1.45)	1.25 (1.09–1.42)	2.92×10−8

^*Cohorts published in Sawalha AH et al. 2008 (8). The Korean cohort included 628 lupus patients and 736 controls; European-derived 1 cohort included 1,080 patients and 1,080 controls.

^**Current study. The European-derived 2 cohort included 1,377 lupus patients and 1,853 controls.