Table 3.
Results of Univariate and Multivariable Logistic Regression Models for the Log Odds of Undergoing Mastectomy As Opposed to BCS
Variable | Univariate Results |
Multivariable Results |
||||
---|---|---|---|---|---|---|
Odds Ratio | 95% CI | P | Odds Ratio | 95% CI | P | |
Preoperative breast MRI, yes v no | 1.9 | 1.5 to 2.4 | < .0001 | 1.7 | 1.3 to 2.2 | < .0001 |
Calendar year | ||||||
1997 v 2003 | 1.8 | 1.4 to 2.3 | < .0001 | 2.0 | 1.5 to 2.6 | < .0001 |
1998 v 2003 | 1.7 | 1.3 to 2.2 | < .0001 | 2.1 | 1.6 to 2.7 | < .0001 |
1999 v 2003 | 1.5 | 1.2 to 1.9 | .0007 | 1.7 | 1.3 to 2.2 | < .0001 |
2000 v 2003 | 1.3 | 1.0 to 1.7 | .02 | 1.4 | 1.1 to 1.8 | .01 |
2001 v 2003 | 1.3 | 1.0 to 1.6 | .06 | 1.4 | 1.1 to 1.8 | .01 |
2002 v 2003 | 1.2 | 1.0 to 1.6 | .08 | 1.4 | 1.1 to 1.8 | .02 |
2004 v 2003 | 1.3 | 1.0 to 1.7 | .02 | 1.4 | 1.1 to 1.8 | .01 |
2005 v 2003 | 1.8 | 1.4 to 2.3 | < .0001 | 1.8 | 1.4 to 2.4 | < .0001 |
2006 v 2003 | 1.7 | 1.3 to 2.2 | < .0001 | 1.7 | 1.3 to 2.2 | .0001 |
Age, years | ||||||
≥ 50 v < 50 | 0.74 | 0.65 to 0.84 | < .0001 | 0.80 | 0.70 to 0.92 | .001 |
TNM stage | ||||||
TNM 1 v 0 | 0.9 | 0.8 to 1.1 | .34 | 0.9 | 0.7 to 1.0 | .09 |
TNM 2 v 0 | 2.1 | 1.8 to 2.4 | < .0001 | 2.0 | 1.7 to 2.4 | < .0001 |
Primary histology | ||||||
Lobular v ductal | 1.6 | 1.4 to 2.0 | < .0001 | 1.6 | 1.3 to 1.9 | < .0001 |
Other invasive v ductal | 1.1 | 0.9 to 1.4 | .40 | 1.2 | 1.0 to 1.6 | .09 |
Breast density | ||||||
4 v 1, 2, 3 | 1.6 | 1.2 to 2.0 | .0001 | 1.5 | 1.1 to 1.9 | .002 |
Unknown v 1, 2, 3 | 1.1 | 1.0 to 1.3 | .04 | 1.0 | 0.9 to 1.1 | .86 |
Concurrent or prior contralateral breast cancer | ||||||
Yes v no | 3.2 | 2.6 to 3.8 | < .0001 | 3.8 | 3.1 to 4.5 | < .0001 |
Laterality | ||||||
Left v right | 1.2 | 1.0 to 1.3 | .007 | 1.2 | 1.0 to 1.3 | .005 |
First-degree family history of breast cancer | ||||||
Yes v no | 1.1 | 1.0 to 1.3 | .05 | 1.2 | 1.0 to 1.3 | .04 |
Abbreviation: MRI, magnetic resonance imaging.