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. 2009 Jul 27;27(25):4082–4088. doi: 10.1200/JCO.2008.19.4225

Table 3.

Results of Univariate and Multivariable Logistic Regression Models for the Log Odds of Undergoing Mastectomy As Opposed to BCS

Variable Univariate Results
Multivariable Results
Odds Ratio 95% CI P Odds Ratio 95% CI P
Preoperative breast MRI, yes v no 1.9 1.5 to 2.4 < .0001 1.7 1.3 to 2.2 < .0001
Calendar year
    1997 v 2003 1.8 1.4 to 2.3 < .0001 2.0 1.5 to 2.6 < .0001
    1998 v 2003 1.7 1.3 to 2.2 < .0001 2.1 1.6 to 2.7 < .0001
    1999 v 2003 1.5 1.2 to 1.9 .0007 1.7 1.3 to 2.2 < .0001
    2000 v 2003 1.3 1.0 to 1.7 .02 1.4 1.1 to 1.8 .01
    2001 v 2003 1.3 1.0 to 1.6 .06 1.4 1.1 to 1.8 .01
    2002 v 2003 1.2 1.0 to 1.6 .08 1.4 1.1 to 1.8 .02
    2004 v 2003 1.3 1.0 to 1.7 .02 1.4 1.1 to 1.8 .01
    2005 v 2003 1.8 1.4 to 2.3 < .0001 1.8 1.4 to 2.4 < .0001
    2006 v 2003 1.7 1.3 to 2.2 < .0001 1.7 1.3 to 2.2 .0001
Age, years
    ≥ 50 v < 50 0.74 0.65 to 0.84 < .0001 0.80 0.70 to 0.92 .001
TNM stage
    TNM 1 v 0 0.9 0.8 to 1.1 .34 0.9 0.7 to 1.0 .09
    TNM 2 v 0 2.1 1.8 to 2.4 < .0001 2.0 1.7 to 2.4 < .0001
Primary histology
    Lobular v ductal 1.6 1.4 to 2.0 < .0001 1.6 1.3 to 1.9 < .0001
    Other invasive v ductal 1.1 0.9 to 1.4 .40 1.2 1.0 to 1.6 .09
Breast density
    4 v 1, 2, 3 1.6 1.2 to 2.0 .0001 1.5 1.1 to 1.9 .002
    Unknown v 1, 2, 3 1.1 1.0 to 1.3 .04 1.0 0.9 to 1.1 .86
Concurrent or prior contralateral breast cancer
    Yes v no 3.2 2.6 to 3.8 < .0001 3.8 3.1 to 4.5 < .0001
Laterality
    Left v right 1.2 1.0 to 1.3 .007 1.2 1.0 to 1.3 .005
First-degree family history of breast cancer
    Yes v no 1.1 1.0 to 1.3 .05 1.2 1.0 to 1.3 .04

Abbreviation: MRI, magnetic resonance imaging.