Table 1 Commercial serological antibody detection tests for the diagnosis of extrapulmonary tuberculosis.
| Name of test (number of studies in review) | Antigen(s) | Source of antigen | Ig class | Laboratory technique | Manufacturer | Address/URL |
|---|---|---|---|---|---|---|
| Anda‐TB* (17) | Antigen 60 | Native | IgG, IgA, IgM | ELISA | Anda Biologicals S.A. | Strasbourg, France www.andabiologicals.com |
| AMRAD ICT TB (1) | 38 kDa and four proprietary antigens | Recombinant | IgG | Immunochromatographic test card | ICT Diagnostics | Balgowlah, NSW, Australia |
| Pathozyme Myco (1) | Lipoarabinomannan (LAM) and 38 kDa | Native LAM and recombinant 38 kDa | IgG | ELISA | Omega Diagnosticshttp://omegadiagnostics.com | Alloa, UK |
| Pathozyme TB Complex Plus (1) | 38 kDa and 16 kDa | Recombinant | IgG | ELISA | Omega Diagnosticshttp://omegadiagnostics.com | Alloa, UK |
| SEVA TB (1) | 31 kDa | Native glycoprotein antigen from culture filtrate of M tuberculosis H37Rv | IgG | ELISA | Jamnalal Bajaj Tropical Disease Research Centre, Mahatma Gandhi Institute of Medical Sciences | Sevagram‐442 102 (Wardha) M S (India) |
Ig, immunoglobulin; ELISA, enzyme‐linked immunosorbent assay; kDa, kilodalton.
*Anda‐TB tests include: IgG (n = 10), IgM (n = 5), IgA (n = 1), IgG and IgM (n = 1).