Table 2.
Summary of the pathways identified from three experiments
| Pathway | P-value | q-value |
| Experiment Ia | ||
| p53 signaling pathway, CCND1 and PCNA | 0.0064 | 0.0362 |
| small Leucine-rich Proteoglycan(SLRP) molecules, Lum | 0.0468 | 0.1131 |
| SREBP control of lipid synthesis | 0.0236 | 0.0319 |
| Experiment IIb | ||
| extrinsic prothrombin activation pathway, F5, F7, Fgb and Fga | 0.001 | 0.004 |
| intrinsic prothrombin activation pathway, F5, F9, Fgb and Fga | 0.0015 | 0.0151 |
| fibrinolysis pathway, serpine 1, Fgb and Fga | 0.0016 | 0.0152 |
| complement pathway | 0.0017 | 0.018 |
| inactivation of Gsk3 by AKT causes accumulation of b-catenin in alveolar macrophages | 0.0024 | 0.0170 |
| platelet amyloid precursor protein pathway, F9 and Serpine 1 | 0.0392 | 0.1788 |
| α-synuclein and Parkin-medicated proteolysis in Parkinson disease, Snca | 0.0455 | 0.1788 |
| Experiment IIIc | ||
| alternative complement pathway | 0.0127 | 0.0644 |
| lectin induced complement pathway | 0.0158 | 0.0209 |
| classical complement pathway | 0.0174 | 0.0209 |
| fibronolysis pathway | 0.0174 | 0.0209 |
| extrinsic prothrombin activation pathway | 0.0205 | 0.0209 |
| complement pathway | 0.0252 | 0.0214 |
aArrayXpath revealed 10 elements in 19 Biocarta pathways. Among the 19 pathways, three are significant.
bArrayXpath has identified 29 elements in 44 Biocarta pathways. Among the 44 pathways, seven are significant.
cArrayXpath revealed 2 (C3 and Fgb) elements in 38 Biocarta pathways. Among the 38 pathways, six are significant.