Table 3.
Proportional Hazards Model of Malignant Transformation for Related Factors(n = 148)1
| Variable | RR | 95%CI | P value | ARR | 95%CI | P value | |
|---|---|---|---|---|---|---|---|
| Age | <=45 years | 1.00 | 1.00 | ||||
| > 45 years | 1.42 | (0.93,2.22) | 0.1007 | 1.42 | (0.90,2.31) | 0.1184 | |
| OPMDs | Hyperkeratosis or epithelial hyperplasia | 1.00 | 1.00 | ||||
| Verrucous hyperplasia | 1.38 | (0.81,2.44) | 0.2304 | 1.23 | (0.66,2.31) | 0.5077 | |
| Epithelial dysplasia | 1.56 | (0.92,2.82) | 0.0991 | 1.51 | (0.86,2.73) | 0.1493 | |
| Location | Buccal2 | 1.00 | 1.00 | ||||
| Tongue | 2.31 | (1.46,3.71) | < 0.001 | 2.41 | (1.43,4.16) | 0.0012 | |
| Other3 | 1.34 | (0.62,2.50) | 0.4103 | 1.37 | (0.62,2.68) | 0.4062 | |
| Smoking | No | 1.00 | 1.00 | ||||
| Yes | 0.77 | (0.47,1.44) | 0.3958 | 0.98 | (0.48,2.31) | 0.9556 | |
| Alcohol use | No | 1.00 | 1.00 | ||||
| Yes | 0.99 | (0.65,1.58) | 0.9809 | 1.10 | (0.68,1.87) | 0.7134 | |
| Areca quid use | No | 1.00 | 1.00 | ||||
| Yes | 0.53 | (0.28,1.34) | 0.1505 | 0.98 | (0.36,2.97) | 0.9682 |
1: OSF cases are excluded in this table
2: Including buccal, vestibule and retromolar
3: Including lip, gingival, palate