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. Author manuscript; available in PMC: 2009 Aug 29.
Published in final edited form as: Eur J Immunol. 2009 Feb;39(2):359–371. doi: 10.1002/eji.200838804

Figure 4. Ovalbumin-specific humoral immunity in TLR-deficient mice inoculated with ovalbumin and flagellin.

Figure 4

Mice (WT and indicated TLR-deficient mice) were immunized with ovalbumin alone or co-injected with 50µg ovalbumin and 50µg flagellin on days 0 and 28. Ovalbumin-specific IgG1 was assayed on day 42 by ELISA. Each point represents the serum IgG1 titer to ovalbumin for an individual mouse. Circles, wild type controls (WT) triangles, indicated TLR-deficient mice. A “+” sign indicates mice were given flagellin in addition to ovalbumin. *-indicates statistically significant difference between WT and KO (p<0.05).