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. Author manuscript; available in PMC: 2009 Aug 29.
Published in final edited form as: Eur J Immunol. 2009 Feb;39(2):359–371. doi: 10.1002/eji.200838804

Figure 7. Effect of loss of TLR5 and MyD88 on flagellin induced activation of splenic DC.

Figure 7

Wild type, TLR5−/−, and MyD88−/− mice were injected once I.P. with 50µg flagellin/100µl PBS/mouse or 100µl PBS/mouse. After 6 hours splenocytes were collected, stained, and analyzed by flow cytometry. Histograms show expression levels of CD80, CD86, and CD40 on CD11chigh gated live cells. Filled gray area, PBS-treated mice; heavy line, flagellin-treated mice. These data are from an individual experiment utilizing spleens pooled from 3 mice per condition. The results are representative of 3 separate experiments that showed an identical patterns of results.