Table 1.
Cases (n = 373) | Controls (n = 309) | p-value* | |
---|---|---|---|
Age, y | 70 ± 13 | 64 ± 12 | <0.0001 |
Male, % | 60 | 64 | 0.24 |
History of MI | 33% | 28% | 0.23 |
History of diabetes | 40% | 33% | 0.06 |
Obese† | 35% | 38% | 0.37 |
Severe LV Dysfunction (EF ≤ 35%)‡ | 22% | 9% | 0.004 |
Using medication with risk of causing Torsades de Pointes (qtdrugs.org List 1) | 7.5% | 3.9% | 0.05 |
Using medication that may prolong QT interval (qtdrugs.org Lists 2 or 3) | 38% | 26% | 0.0005 |
Any medication from Lists 1-3 | 43% | 27% | <0.0001 |
p-value from t-tests for continuous variables and chi-square tests for categorical variables.
BMI ≥30; BMI available for 309 cases and 291 controls
EF from echo, angiogram, or MUGA for 188 cases and 116 controls