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. Author manuscript; available in PMC: 2009 Aug 30.
Published in final edited form as: Genet Med. 2008 Sep;10(9):668–674. doi: 10.1097/GIM.0b013e3181833793

Table 2.

Contrasting results between the two candidate genes/association analyses.

Locus Gene SNP CLP Data (p-value) CLP + Dental Anomalies Data (p-value)
Loci where association is present in both clefts and clefts + dental anomalies data
9q22.33 ANKS6 rs4742741 0.001 0.0004
CYLC2 rs843258 0.02 0.008
GABRB2 rs1930135 0.01 0.009
TGFBR1 rs418919 0.005 0.02
FOXE1 rs1020884 0.01 0.01
FOXE1 rs4743088 0.01 0.01
17q21.1 ERBB2 rs1810132 0.0006 0.0006
ITGB3 rs2015729 0.002 0.003
ITGB3 rs2292699 0.01 0.005
1q32.3-q41 IRF6 rs2013162 0.002 0.002
IRF6 rs674433 0.001 0.01
6q21-q23 SCML4 rs9320231 0.01 0.006
BC039503 rs6921044 0.01 0.006
TCF21 rs969282 0.02 0.008
LAMA4 rs971402 0.003 0.008
MTRFL1 rs2503791 0.003 0.009
TAAR6 rs7772821 0.005 0.01
2p13 TGFA rs377122 0.04 0.03
Loci where association is stronger in the clefts + dental anomalies than that in the clefts data
5q34 FGF18 rs4559013 0.09 0.05
FGF18 rs3934591 0.1 0.05
14q24.3-q31.1 DPF3 rs2536143 0.18 0.03
NRXN3 rs221430 0.32 0.04
15q11.2-q12 SLC12A5 rs2879515 0.06 0.01
GABRB3 rs878960 0.06 0.02
GABRB3 rs1426223 0.06 0.05
LIPC rs690 0.02 0.04
20q13 AHCY rs819133 0.06 0.02
BMP7 rs6123674 0.07 0.04
21q22.11 GART rs4817579 0.16 0.02