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(A) DR5 expression on AB1-HA tumor cells in vitro. (B) Tumor growth curves in CY-treated and untreated TRAIL-deficient mice, compared with immunocompetent mice and nude mice. Data shown are mean±SEM (n = 10) from two combined experiments. Tumor cells were inoculated at day 0 and treated with CY at day 10. ** P<0.005 when CY in BALB/c is compared with CY in TRAIL-deficient mice.
