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. 2009 Sep 10;4(9):e6982. doi: 10.1371/journal.pone.0006982

Figure 7. Rescue of CY anti-tumor efficacy in nude mice by anti-DR5 antibodies.

Figure 7

Tumor-bearing athymic nude mice (inoculated at day 0) were treated with CY or with PBS at day 9 (a) or day 7 (b) after tumor cell inoculation and were treated with anti-DR5 antibody (clone MD5-1) or PBS at day 8, 12 and 16 after tumor cell inoculation. Data shown are mean±SEM (n = 5/group for each experiment). * P<0.05 when CY is compared with CY + anti-DR5. The effect of anti-TRAIL Ab without CY is shown in (b). Two mice were disqualified from the graph as they were found dead early in the experiment.