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. 2009 Sep 9;4(9):e6966. doi: 10.1371/journal.pone.0006966

Table 1. Physiological effects of dsRNA-mediated silencing of α-glucosidase.

Accessiona Putative Function b E-value Organism Similarity Identities (%)
FJ236283 Alpha-glucosidase 3e-145 Rhodnius prolixus 100
XP_001851486 Alpha-glucosidase 8e-102 Culex quinquefasciatus 70
XP_001869889 Alpha-amylase 4e-93 Culex quinquefasciatus 64
XP_001847532 Alpha-glucosidase 5e-90 Culex quinquefasciatus 64
XP_001656785 Alpha-amylase 7e-101 Aedes aegypti 69
CAA60858 Maltose like protein Agm2 4e-86 Anopheles gambie 59
AAB82328 Maltase 2 1e-71 Drosophila virilis 52
PDBc ZEO_A Alpha-glucosidase 6e-47 Geobacillus sp. 27
PDB 1UOK_A Oligo-1,6-Glucosidase 1e-25 Bacillus cereus 27
CAA87020 Alpha-glucosidase 2e-22 Saccharomyces cerevisiae 24

The insects were injected with 2 µL of 100 mM PBS pH 7.4 or dsLacZ (controls) and dsα-glu (2 or 10 µg/female); mortality and oviposition were monitored 4 days after feeding. In all panels, results are means ±SEM (n = 70). The insects injected with 10 µg dsα-glu, analyzed 4 days feeding, were significantly different from control insects injected with both PBS and dsLacZ and also analyzed 4 days after feeding *(P<0.05).

a

Access number to GenBank database.

b

Function expected according the Blastx sequence results similarity in GenBank database.

c

Protein Data Bank.