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. 2000 Apr 22;320(7242):1097–1102. doi: 10.1136/bmj.320.7242.1097

Table 3.

Relation with lifelong smoking status in male doctors who died of or with dementia versus matched controls

Type of dementia No of cases (controls)
Heterogeneity Risk ratio (95% CI)
Continuing smokers Long term ex-smokers* Never smoked regularly Continuing v ex-smokers* Continuing v never smokers Ex*v never smokers
Probably or definitely due to Alzheimer's disease 147 (591) 156 (665) 67 (224) χ2=2.2, P=0.3 1.07 (0.83 to 1.38) 0.83 (0.60 to 1.16) 0.78 (0.56 to 1.10)
Vascular or Lewy body  43 (187)  44 (162) 16 (63) χ2=0.5, P=0.8 0.83 (0.51 to 1.34) 0.94 (0.49 to 1.82) 1.07 (0.57 to 2.02)
Any 190 (778) 200 (827) 83 (287) χ2=1.6, P=0.4 1.01 (0.81 to 1.27) 0.85 (0.63 to 1.14) 0.84 (0.63 to 1.13)
*

Stopped smoking on average 34 years.