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Antiscratch dose of nalfurafine has no effect on locomotion. Nalfurafine (0.02 mg/kg) does not markedly affect locomotion of mice (n=8) whereas the higher dose of nalfurafine (0.04 mg/kg) antagonizes locomotion significantly (p<0.01 compared to control and 0.02 mg/kg of nalfurafine).
