Skip to main content
. Author manuscript; available in PMC: 2009 Aug 31.
Published in final edited form as: J Mol Biol. 2008 May 17;381(1):89–101. doi: 10.1016/j.jmb.2008.05.018

Figure 1.

Figure 1

A. Assembly of the Biotin Operon Repression Complex occurs by coupled dimerization and DNA binding. Binding of the effector, bio-5'-AMP, induces repressor dimerization, which is a prerequisite to site-specific DNA binding to the biotin operator sequence. B. Model of the apoBirA structure with the positions of the four partially disordered loops highlighted. The models were created in MolMol (35) using PDB files 1hxd and 2ewn as input.