Strong interferences and enhancements are shown in red (2 to 5.2), while weak interferences and enhancements are displayed in green (1.5 to 1.9). The various symbols reflect different analogs: AαS or GαS analog (star), 7-deazaAαS (sphere), N6-methylAαS (square), DAPαS (triangle), 2’dAαS or 2’dGαS analogs (grid) and IαS (diamond). Open symbols represent enhancements and closed symbols indicate interferences.