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. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: Neuropharmacology. 2009 May 28;57(3):332–342. doi: 10.1016/j.neuropharm.2009.05.004

Figure 4. Inhibition curves for [125I]α-bungarotoxin and [125I]epibatidine binding.

Figure 4

Inhibition of 0.5 nM [125I]α-bungarotoxin binding in total membrane preparation from hippocampus of C57BL/6J mice (A). Data was fitted to a single site inhibition curve. Inhibition of 200 pM [125I]epibatidine binding in total membrane preparation from inferior colliculus of wilt-type (B), β2-/- (C) and β4-/- (D) mice. Data was fitted to a two site inhibition curve for wild-type samples and one site inhibition curve for the two null mutant mice.