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. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: Neuropharmacology. 2009 May 28;57(3):332–342. doi: 10.1016/j.neuropharm.2009.05.004

Figure 6. Determination of [125I]α-bungarotoxin binding sites in whole membranes.

Figure 6

DBA/2J mice were chronically intravenously infused with 3-IC 0.2 mg/kg/h for 7 days. After treatment the brains were removed and total brain membranes were obtained. To determine α7* nAChR binding sites we incubated the particulate fractions from brain regions with 1 nM [125I]α-bungarotoxin. Non-specific sites were determined by adding 1 mM nicotine (* p < 0.05, Student's t test, n=3). Abbreviations: cerebral cortex (Cx), striatum (St), hippocampus (Hp).