Table 3.
ADC deficit (defined as ADCi/ADCc) and Na+ accumulation in individual brainsa
| Rat #b | ADCi/ADCc vs. Slope | ADCi/ADCc vs. [Na+]EFP | ||
|---|---|---|---|---|
| R | P | R | P | |
| 1 | 0.20 ± 0.15 | > 0.6 | NA | NA |
| 2 | NA | NA | 0.54 ± 0.09 | > 0.3 |
| 4 | −0.80 ± 0.04 | > 0.1 | 0.30 ± 0.06 | > 0.7 |
| 5 | 0.60 ± 0.13 | > 0.1 | −0.70 ± 0.11 | > 0.07 |
| 6 | −0.05 ± 0.14 | > 0.8 | 0.93 ± 0.04 | < 0.05* |
| 7 | −0.20 ± 0.13 | > 0.6 | NA | NA |
| 8 | 0.55 ± 0.09 | > 0.4 | 0.58 ± 0.09 | > 0.4 |
| 9c | - | - | 0.40 ± 0.10 | > 0.5 |
| 10 | 0.09 ± 0.16 | > 0.8 | −0.05 ± 0.18 | > 0.9 |
a
Na+ accumulation was characterized either by the [Na+]br increase rate measured by MRI (Slope, left columns) or, independently, by [Na+]br at the end of experiment as measured directly by emission flame photometry ([Na+]EFP right columns). The data were obtained from ROIs characterized as ischemic by ADC (i.e., ADCi/ADCc < 0.8). R, correlation coefficient ± SD; P, statistical significance of the correlation.
b
For the rat #3, ADC data were unavailable.
c
Slope values are not statistically significant.
*
Statistically significant.
NA = not available.