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. 2009 Sep;23(9):2844–2854. doi: 10.1096/fj.08-128843

Figure 8.

Figure 8.

Knockdown of geranylgeranyl transferase II in zebrafish mimics lovastatin-induced myofiber damage. A) Myosin heavy-chain staining of representative control morpholino-injected or z-GGTase I or II-injected zebrafish embryos (top), and myofiber diameter (bottom). B) Quantitation of muscle damage. Embryos/group: 100, 98, 102 for controls and 98, 96, 100 for z-GGT I knockdowns at 0, 8, 16 ng morpholino/embryo, respectively; 75, 91, 83 for controls and 75, 88, 95 for z-GGT II knockdowns at 0, 8, 16 ng morpholino/embryo, respectively.