Table 2.
Differentially expressed HDL3 proteins detected by spectral counting.
| Protein Identification Number1 |
Protein Name | CAD2 | CAD + Niacin/Statin2 |
Average Ratio (on therapy to off therapy) 3 |
P value |
|---|---|---|---|---|---|
| IPI00022733 | PLTP | 0 | 3.0 (2.7) | >3 | 0.02 |
| IPI00480119 | Apolipoprotein F | 3.8 (1.1) | 5.2 (0.75) | 1.4 | 0.005 |
| IPI00291262 | Clusterin (Apolipoprotein J) |
0.3 (0.8) | 1.8 (2.2) | 6.2 | 0.12 |
| IPI00021842 | Apolipoprotein E | 15 (3.5) | 11 (2.1) | 0.74 | 0.002 |
| IPI00021856 | Apolipoprotein C- II |
15 (5.5) | 11 (4.2) | 0.80 | 0.13 |
| IPI00021841 | Apolipoprotein A-I | 242 (48) | 257 (45) | 1.08 | 0.43 |
1
Protein identification numbers are from the International Protein Index database, v3.01.
2
Numbers shown are total number of peptides identified (SD) for spectral counting.
3
Average ratios were calculated from the individual ratio for each protein for each subject at baseline and at 1 yr niacin/statin therapy.