Relationship between clinical symptoms and caudate volume among MDD subjects (N=26).
Scatterplot and Pearson correlation between residualized right caudate volume (adjusted for age and gender) and (A) total BDI score (r=-0.579, p<0.002); and (B) anhedonic BDI subscore (r=-0.635, p<0.0001) among MDD subjects. Similar correlations emerged for the left caudate (total BDI: r=-0.489, p<0.015; anhedonic BDI: r=-0.553, p<0.004). The anhedonic BDI subscore was computed by summing item #4 (loss of pleasure), #12 (loss of interest), #15 (loss of energy), and #21 (loss of interest in sex). Cd = Caudate.