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PrPCJD patterns either present (+) or not present (−). (Comparison of the PrPCJD patterns in vCJD and kuru by immunohistochemistry.)
| PrPCJD pattern | vCJD | kuru |
|---|---|---|
| florid plaques | + | − |
| linear/granular diffuse plaques | + | − |
| dendritic | + | + |
| perineuronal | + | + |
| cortical L3-5 laminar | − | + |
| accentuation | ||
| linear white matter in the brain stem and the spinal cord | + | + |
| granular intracytoplasmic | + | − |
