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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Biomaterials. 2009 Aug 5;30(30):6006–6016. doi: 10.1016/j.biomaterials.2009.07.015

Fig. 4.

Fig. 4

The cytotoxicity of PEG5k-CA8 nanoparticles with or without PTX loading against normal human cells and ovarian cancer cells. (A) Cytotoxicity of blank PEG5k-CA8 NPs and cremophor:ethanol vehicle on HFF1 human fibroblast cells. C1 and C2 are the estimated blood concentratoin of PEG5k-CA8 and cremophor:ethanol after in vivo administration, respectively, assuming the blood volume of an average person is 6L. The anticancer effects of PTX-loaded PEG5k-CA8 NPs were performed on ES-2 cells (B) and SKOV3-luc cells (C) compared with Taxol®and Abraxane®.