Half-normal plot showing the effect of factors on the (a) protein release rate in phase I (burst release), (c) protein release rate in phase II (sustained burst release), (e) protein release rate in phase III (plateau release), and (h) thermoresponsiveness of the hydrogels (up to 8 hrs); 3D surface plot showing the effect of factors on the (b) protein release rate in phase I (burst release), (d) protein release rate in phase II (sustained burst release), (f, g) protein release rate in phase III (plateau release), and (i) thermoresponsiveness of the hydrogels (up to 8 hrs)