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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: Cell Signal. 2009 Jun 26;21(11):1569–1578. doi: 10.1016/j.cellsig.2009.06.003

Figure 5. Deletion of the PH domain decreases LARG activity in cells.

Figure 5

(A) Schematic representation of LARG constructs used in cell-based assays. (B) Normalized SRE.L luciferase activities of the indicated constructs. Data represents the mean ± SD of three independent experiments, each measured in triplicate (***, p<0.001). (C) Distribution of LARG constructs in HEK293T cells. GFP-ΔC and GFP-ΔPH/C show pronounced nuclear distribution. Scale bar: 10 µm.