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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: Cell Signal. 2009 Jun 26;21(11):1569–1578. doi: 10.1016/j.cellsig.2009.06.003

Figure 6. Fusion with two tandem PLCδ1 PH domains rescues the activity of the F1098D mutant.

Figure 6

(A–C) Normalized SRE.L luciferase activities of the LARG (A) FL, (B) DH/PH, and (C) ΔC proteins (WT and F1098D) in the presence or absence of two PH domains from PLCδ1 fused to the C-terminus. Data represents the mean ± SD of 2 independent experiments, each measured in triplicate. (D–F) Confocal microscopy images of COS-7 cells transfected with GFP-LARG (D) FL, (E) DH/PH, and (F) ΔC proteins. Scale bar: 10 µm.