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. 2009 Sep 11;4(9):e6944. doi: 10.1371/journal.pone.0006944

Figure 3. Importance of the transcriptional function of the S-phase checkpoints.

Figure 3

Wild-type (yFS625), cds1Δ (yFS627), cds1Δ cdc10-2E (yFS629), rad3Δ (yFS628), rad3Δ cdc10-2E (yFS630) and nmt1:pyp3 mik1Δ (yFS632) cells were treated with 10 mM HU or 0.03% MMS for the indicated times and then plated. Colonies were counted after 7 days. The relative percentage survival was calculated by dividing the number of viable colonies from each timepoint by the number of viable colonies before the addition of HU or MMS. n = 3; error bars indicate SEM and are often obscured by the data symbols.