Table 1. OLPs targeted in the current study (by ≥2 subjects) that are not found on the Best Defined Epitope (BDE) list.
| OLP Sequence aligned to clade B consensus (below) | Overlapping Peptide (OLP) | Env position (HXB2) | No. of Responders (n = 61) | Previous descriptions of epitopes in the region |
| LVSGFLALAWDDLRN ----D---------I------------- | OLP-149 | 749–63 | 11 (18.0%) | 20mer (742–61) includes this epitope, no HLA |
| GRSIRLVSGFLALAW D---G-----D---------I---- | OLP-148 | 744–58 | 9 (14.8%) | |
| EQDRGRSIRLVSGFL --R----D---G-----D----- | OLP-147 | 739–53 | 6 (9.8%) | |
| ELLGHSSLKGLRLGW -------deleted............. | OLP-156 | 783–97 | 6 (9.8%) | 786–794 (different sequence) |
| LGNLLLYWGRELKTS WW---Q-----SQ-----N- | OLP-160 | 796–810 | 5 (8.2%) | 799–807, different epitope |
| IKQLQARVLAVERYL ---------------------------- | OLP-114 | 573–87 | 5 (8.2%) | 19mers (570–589, 572–590) |
| EVHNVWATHACVPTD ------------------------------ | OLP-13 | 64–78 | 4 (6.5%) | described as 20mer (62–80), no HLA |
| VRQGYSPLSFQTLTP -----------------------RL-- | OLP-141 | 708–22 | 4 (6.5%) | nothing |
| IYMENVTEEFNMWKN VVL---------N------------- | OLP-17 | 84–98 | 4 (6.5%) | A*11, A*68, clade B version |
| NITNNITNSITNSSV -----TS--RDKVQKEYA | OLP-27 | 160–74 | 4 (6.5%) | nothing |
| LTVWGIKQLQARVLA ----------------------------- | OLP-113 | 568–82 | 3 (4.9%) | see OLP-114 |
| LDCSYNITNNITNSI KN----F------TS--RDKV | OLP-26 | 155–69 | 3 (4.9%) | 156–65 Cw8 |
| QHLLKLTVWGIKQLQ --------Q------------------- | OLP-112 | 563–77 | 2 (3.3%) | 565–573 (A2) |
| AIEAQQHLLKLTVWG -----------------Q---------- | OLP-111 | 558–72 | 2 (3.3%) | closest is 557–65 w R in front |
| PNPQEIYMENVTEEF ---------VVL----------N- | OLP-16 | 79–93 | 2 (3.3%) | 78–86 B*3501, w D in front |
| SPLSFQTLTPNPRDP -------------RL-A----G-- | OLP-142 | 713–27 | 2 (3.3%) | nothing |
Optimal epitopes = underlined.