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. Author manuscript; available in PMC: 2010 Mar 15.
Published in final edited form as: Biosens Bioelectron. 2008 Nov 1;24(7):1995–2001. doi: 10.1016/j.bios.2008.10.012

Fig. 6.

Fig. 6

Example of real-time, multiplexed and specific DNA detection using the active CMOS biosensor array. Site A is functionalized with probe P1 and site B with P2. Target T1 is added, followed by T2 at a later time. Hybridization is observed at site A, where P1 hybridizes with fully-complementary T1, while no hybridization is seen at site B. After T2 is added, hybridization is observed at site B while the signal at site A remains constant. The extent of hybridization at sites A and B as a function of time is also shown.